Cellular proteins mediate 5′–3′ end contacts of Norwalk virus genomic RNA
نویسندگان
چکیده
منابع مشابه
Specific binding of host cellular proteins to multiple sites within the 3' end of mouse hepatitis virus genomic RNA.
The initial step in mouse hepatitis virus (MHV) RNA replication is the synthesis of negative-strand RNA from a positive-strand genomic RNA template. Our approach to begin studying MHV RNA replication is to identify the cis-acting signals for RNA synthesis and the proteins which recognize these signals at the 3' end of genomic RNA of MHV. To determine whether host cellular and/or viral proteins ...
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Forty-four nucleotides at the 5' terminus of the genomic RNA of Sindbis virus can form a stable stem-loop structure and have been shown previously to be important for viral replication. The structure formed by the complement of this sequence at the 3' end of the minus-strand RNA has been proposed to be a promoter for RNA replication and as such might be bound in a specific fashion by proteins o...
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ژورنال
عنوان ژورنال: Virology
سال: 2009
ISSN: 0042-6822
DOI: 10.1016/j.virol.2009.02.041